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Toxicity in animal research with artemether Artesunate First trimester: Avoid Atenolol May cause intrauterine progress restriction, neonatal hypoglycaemia, and bradycardia; threat greater in extreme hypertension Atropine Not identified to be dangerous Azathioprine Transplant sufferers should not discontinue azathioprine on turning into pregnant; use in being pregnant should be supervised in specialist models; there isn't any evidence that azathioprine is teratogenic Azithromycin Use only if potential profit outweighs risk Beclometasone Benefit of remedy, for instance in asthma, outweighs risk 492 Appendixes Benzathine benzylpenicillin Not known to be harmful Benzylpenicillin Not known to be harmful Betamethasone Benefit of remedy, for instance in asthma, outweighs risk Bleomycin Avoid (teratogenic and carcinogenic in animal research); see additionally part 10 Bupivacaine Third trimester: With massive doses, neonatal respiratory despair, hypotonia, and bradycardia after paracervical or epidural block Calcium folinate Manufacturer advises use only if potential benefit outweighs threat Carbamazepine First trimester: Risk of teratogenesis together with increased risk of neural tube defects (counselling and screening and enough folate dietary supplements suggested, for example 5 mg day by day); risk of teratogenicity larger if multiple antiepileptic used; see additionally part 4. 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